Goat IgG-SAP is the perfect control for use with secondary conjugates Mab-ZAP, Rab-ZAP, Hum-ZAP, Rat-ZAP, Anti-M-ZAP, Hug-M-ZAP, Fab-ZAP mouse, Fab-ZAP human, Fab-ZAP rat, Fab-ZAP rabbit and gPIG-ZAP. The secondary antibody conjugates are used with a primary antibody (a mouse monoclonal, rabbit polyclonal, human monoclonal, rat monoclonal, or IgM mouse monoclonal) to determine if the primary antibody can internalize saporin and would, therefore, be suitable for conjugation as a primary immunotoxin. Goat IgG-SAP, used in place of the secondary antibody conjugate, will give a definitive baseline for comparison of the activity of the primary antibody to internalize.
Goat IgG-SAP serves as a control for goat IgG-containing immunolesioning agents.
To view protocol(s) for this and other products please visit: www.ATSbio.com/support/protocols
Advanced Targeting Systems(ATS)位于美国加州圣地亚哥, 成立于1994年。 公司发起人Douglas Lappi和Ronald Wiley博士在实验室开发出先进的分子神经外科学研究技术。ATS主要生产用于科研和药物研发的靶向试剂,公司在疼痛和药物转运的研究及临床治疗的两个产品已获专利保护。目前,产品包括靶向毒素 (可提供基底前脑胆碱能神经元、去甲肾上腺素能和肾上腺素能神经元、巨噬细胞和小胶质细胞的特异性损伤试剂等)、二抗生物素、神经元抗体、神经递质抗体、蛋白质和荧光结合物、免疫毒素对照等。