CD4 is a cell-surface glycoprotein found on mature helper T-cells, immature thymocytes, monocytes, and macrophages. Some cytotoxic T-cells express CD4 as well. The T-cell population in normal blood is approximately 65% CD4+. A mature T-cell expresses either CD4 or CD8, but not both. During an early stage of development T-cells have both CD4 and CD8 receptors but are differentiated in the thymus.
Mouse anti-human CD4 is conjugated to FITC and purified by ion exchange chromatography. The protein concentration is 1 mg/ml in PBS after reconstitution.
Reported to be effective as a blocking and staining antibody. Blocks binding of HIV to CD4.
To view protocol(s) for this and other products please visit: www.ATSbio.com/support/protocols
Advanced Targeting Systems(ATS)位于美国加州圣地亚哥, 成立于1994年。 公司发起人Douglas Lappi和Ronald Wiley博士在实验室开发出先进的分子神经外科学研究技术。ATS主要生产用于科研和药物研发的靶向试剂,公司在疼痛和药物转运的研究及临床治疗的两个产品已获专利保护。目前,产品包括靶向毒素 (可提供基底前脑胆碱能神经元、去甲肾上腺素能和肾上腺素能神经元、巨噬细胞和小胶质细胞的特异性损伤试剂等)、二抗生物素、神经元抗体、神经递质抗体、蛋白质和荧光结合物、免疫毒素对照等。