Somatostatin Receptor-4 is one of five receptor subtypes termed SSTR1-5. They are G-protein-coupled receptors characterized by seven transmembrane domains with an extracellular amino terminal domain and an intracellular carboxy terminus. These receptors function in the regulation of numerous physiological processes such as the secretion of insulin, glucagon, and growth hormone, as well as cell growth induced by neuronal excitation in both the central and peripheral nervous systems. Somatostatin receptors are activated via somatostatin secretion in nerve and endocrine cells.
This peptide corresponds to a sequence from the extracellular domain of Somatostatin Receptor-4 (SSTR4). 100 micrograms of the peptide is diluted into 500 microliters of PBS containing 100 micrograms BSA.
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Advanced Targeting Systems(ATS)位于美国加州圣地亚哥, 成立于1994年。 公司发起人Douglas Lappi和Ronald Wiley博士在实验室开发出先进的分子神经外科学研究技术。ATS主要生产用于科研和药物研发的靶向试剂,公司在疼痛和药物转运的研究及临床治疗的两个产品已获专利保护。目前,产品包括靶向毒素 (可提供基底前脑胆碱能神经元、去甲肾上腺素能和肾上腺素能神经元、巨噬细胞和小胶质细胞的特异性损伤试剂等)、二抗生物素、神经元抗体、神经递质抗体、蛋白质和荧光结合物、免疫毒素对照等。